Pulmonary Hypertension in Hemodialysis Patients
Mitra Mahdavi-Mazdeh1, Seyed Alijavad-Mousavi2, Hooman Yahyazadeh3, Mitra Azadi4, Hajar Yoosefnejad4, Yoosef Ataiipoor5
1 Department of Nephrology, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Pulmonary Medicine, Iran University of Medical Sciences, Tehran, Iran
3 Department of Medicine, Iran University of Medical Sciences, Tehran, Iran
4 Department of Cardiology, Iran University of Medical Sciences, Tehran, Iran
5 Department of Nephrology, Iran University of Medical Sciences, Tehran, Iran
Abstract
The aim of this study was to evaluate the prevalence of primary pulmonary hypertension (PHT) among hemodialysis patients and search for possible etiologic factors. The prevalence of PHT was prospectively estimated by Doppler echocardiogram in 62 long-term hemodialysis patients on the day post dialysis. PHT (> 35 mm Hg) was found in 32 (51.6%) patients with a mean systolic pulmonary artery pressure of 39.6 ± 13.3 mmHg. The hemoglobin and albumin levels were significantly lower in the PHT subgroup (11.1 ± 1.86 vs 9.8 ± 1.97 g/dL and 3.75 ± 0.44 vs 3.38 ± 0.32 g/dL, p = 0.01 and 0.02, respectively). Our study demonstrates a surprisingly high prevalence of PHT among patients receiving long-term hemodialysis. Early detection is important in order to avoid the serious consequences of the disease.
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